Is this in DC or Civilization scale? Andromeda spanned ~3 galaxies however the strongest weapons were Solar System level, with eventual galactic destruction over an undetermined timeframe (magog worldship wiped clean an entire galaxy of stars) WH40k is ~Galaxy level in civilization scale at most, the old ones got decimated and I'm not sure daemons fall under any sort of civilization scale Xeelee Sequence is at least multi galactic in scale I think? not sure on maximum DC Manifold Series is multiversal in scale