Frieza is number 1 obviously. Even before his actual introduction we knew he wasn't to be fucked with. We know this because all of his henchmen AND Vegeta, all ruthless themselves, weren't trying to fuck with him. Vegeta wanted to make sure he was immortal before he fought the nigga because he knew he was gonna catch the fade. Then you have his multiple transformations. Every time you thought you had this him sike, this isn't even my final form. While he's moved more toward the comic relief side recently he's still one of the villain GOATs 2nd place I'd have Makima/Meruem. On the one hand you have Makima who right from the start they make it a note that somethings off about her but you never really know what. Then as soon as the series climax hits she slaps you in the face with a wet fish and reveals she's had everyone doing what she wanted from the start. The governments of the world all came together and made a deal with the devil that bodied most of the planet trying to get...
