When it comes to cosmology, nah, the overall cosmology as it's been detailed and portrayed still applies to IG Thanos, even if those events happened before Marvel has fully fleshed out it's cosmology, later stuff just serves to make those events more impressive in the long run.Problem I see with Thanos is his best scaling feats all come from Starlin's stuff. Him fighting Odin, Galactus, stomping with the IG (could be wrong about the IG), etc. All comes from his Starlin run (Or Thanos Wins). Starlin's cosmology is detailed out over the course of his comics and it isn't the same, nor is it as impressive or complex as other Marvel stories portray the cosmology, which wouldn't be a problem if Starlin wasn't so insular with his cosmology and storylore and is basically writing his own verse and franchise.
When it comes to base Thanos, it ultimately depends on what's most consistent between writers, his durability is notoriously high, but he was getting fairly smacked around in both of those fights, physically, anyhow.
The mind fuck/telepathic shit with Thanos and Galan is really fucking stupid though, and OOC for Galactus.